Systems biology of neurodegenerative diseases
نویسندگان
چکیده
منابع مشابه
The Cell and Molecular Biology of Neurodegenerative Diseases: An Overview
In this research topic, the primary focus is on understanding the cellular and molecular mechanisms in the pathogenesis of different neurodegenerative disorders. These include Alzheimer’s disease (AD), Parkinson’s disease (PD), and polyglutamine (polyQ) expansion diseases. To date, no cure exists for these disorders and it is paramount that research efforts continue to focus on understanding th...
متن کاملDissecting the Molecular Mechanisms of Neurodegenerative Diseases through Network Biology
Neurodegenerative diseases are rarely caused by a mutation in a single gene but rather influenced by a combination of genetic, epigenetic and environmental factors. Emerging high-throughput technologies such as RNA sequencing have been instrumental in deciphering the molecular landscape of neurodegenerative diseases, however, the interpretation of such large amounts of data remains a challenge....
متن کاملneurodevelopmental basis of neurodegenerative diseases
the human brain is composed of several interconnected, functionally distinct structures and much debate has surrounded the basic question of how these structures evolve. brain development begins in early gestation. between 4 weeks and 9 months, brain undergoes rapid development. there are six stages of nervous system development. brain increases connections between birth and 21 years of age. ab...
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ژورنال
عنوان ژورنال: Integrative Biology
سال: 2015
ISSN: 1757-9694,1757-9708
DOI: 10.1039/c5ib00031a